Welcome to the MzH Lab

The laboratory of Gerd Meyer zu Hörste, MD (the MzH lab) is part of the Department of Neurology at the University Hospital Münster and the University of Münster in Germany. We employ a wide range of experimental techniques to study disease mechanisms in neuro-immunological disorders. The specific aims of our research are:

  1. Understand the interaction between T helper cells and parenchymal cells of the nervous system.

  2. Characterize the interaction between recently discovered subsets of T helper cells with B cells in autoimmunity of the nervous system.

  3. Define how the brain microenvironment shapes the phenotype and function of immune cells.

Areas of special interest include multiple sclerosis, inflammatory myopathy and inflammatory neuropathy and their animal models. In addition, we actively develop novel techniques and adapt them to neuroimmunological diseases including high-throughput single cell expression profiling and proteomic profiling.

Datasets

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Meninges

Meninges

Single-cell profiling of CNS border compartment

Neuro-COVID

Neuro-COVID

Single-cell atlas of cerebrospinal fluid in Neuro-COVID and controls

Murine peripheral nerve

Murine peripheral nerve

Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity

Neurosarcoidosis

Neurosarcoidosis

Differentiating neurosarcoidosis from multiple sclerosis using flow cytometry.

Recent Publications

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Meet the Team

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Carolin Lewe

Bachelor student

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Frederike Straeten

Neurology resident

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Gerd Meyer zu Hörste

Attending Neurologist, Principial investigator

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I-Na Lu

PostDoc

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Julia Tietz

Technical assistant

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Luca Marongiu

Master student

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Michael Heming

Neurology resident

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Svea Haessner

Neurology resident

Funding

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