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Automatic
T cell exhaustion
Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma
BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare lymphoma of the central nervous system, usually of diffuse large …
Michael Heming
,
Svea Haessner
,
Jolien Wolbert
,
I-Na Lu
,
Xiaolin Li
,
Benjamin Brokinkel
,
Michael Müther
,
Markus Holling
,
Walter Stummer
,
Christian Thomas
,
Andreas Schulte-Mecklenbeck
,
Flavia de Faria
,
Marlon Stoeckius
,
Stephan Hailfinger
,
Georg Lenz
,
Kornelius Kerl
,
Heinz Wiendl
,
Gerd Meyer zu Hörste
,
Oliver M. Grauer
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Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid
We utilized single-cell sequencing and examined the immune cell profiles from the cerebrospinal fluid of Neuro-COVID patients and discovered an expansion of dedifferentiated monocytes and exhausted CD4+ T cells.
Michael Heming
,
Xiaolin Li
,
Saskia Räuber
,
Anne K Mausberg
,
Anna-Lena Börsch
,
Maike Hartlehnert
,
Arpita Singhal
,
I-Na Lu
,
Michael Fleischer
,
Fabian Szepanowski
,
Oliver Witzke
,
Thorsten Brenner
,
Ulf Dittmer
,
Nir Yosef
,
Christroph Kleinschnitz
,
Heinz Wiendl
,
Mark Stettner
,
Gerd Meyer zu Hörste
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